Chromatin, Development and Cancer

English     Français     Русский     Contact     Gallery     GDRI     Site Map      
Scientific projects     Staff     Job opportunities     Collaborations & funding      
 

 

Chromatin,  Development and Cancer

 

Yegor Vassetzky 

 

Chromatin, Development and Cancer lab is a part of the CNRS UMR-8126 (Molecular Interactions and Cancer) department at the Gustave Roussy Institute, one of the biggest European cancer research centers, located nearby Paris.

 

We're working on the role of chromatin organization in normal cells and in some diseases, such as fascio-scapulo-humeral dystrophy (FSHD) and cancer.

Selected Recent Publications:

 

 

Razin, S.V., Gavrilov, A.A., Pichugin, A., Lipinski, M., Iarovaia, O.V. and VASSETZKY, Y.S. (2011) Transcription factories in the context of the nuclear and genome organization. Nucl. Acids. Res., 1–8 doi:10.1093/nar/gkr683

Dmitriev, P., Petrov , A., Ansseau, E.,  Charron, S.,  Coppée, F., Belayew, A., Carnac, G., Turki, A., Laoudj, D., Lipinski, M., and VASSETZKY, Y.S., (2011) The Krüppel-like factor KLF15 as a key actor in upregulation of the 4q35 genes in FSHD muscles, J. Biol. Chem., DOI:10.1074/jbc.M111.254052

Eivazova E. R., Gavrilov A., Pirozhkova I., Petrov A., Iarovaia O.V., Razin S. V., Lipinski M., VASSETZKY Y. S. (2009) Interaction in vivo between the two matrix attachment regions flanking a single chromatin loop. J. Mol.Biol., 386: 929-937 pdf

Dmitriev P., Lipinski, M. and VASSETZKY, Y (2009) Pearls in junk: dissecting the molecular pathogenesis of facioscapulohumeral muscular dystrophy. Neuromuscular Disorder, 19:17-20 pdf

Petrov A., Allinne J., Pirozhkova, I., Laoudj, D., Lipinski, M., and VASSETZKY, Y.S.(2008) Nuclear matrix attachment site in the 4q35 locus has an enhancer-blocking activity: implications for the facioscapulohumeral dystrophy. Genome Research, 18:39-45. pdf 

Razin, S.V., Iarovaia, O;,Sjakste, N., Sjakste,  T., Bagdoniene, L.,  Rynditch, A.V., Eivazova,  E.R., Lipinski, M., and VASSETZKY, Y.S. (2007) Chromatin domains and regulation of transcription. J. Mol. Biol, 369:597-607. pdf 

Petrov, A. Pirozhkova, I., Carnac, G., Laoudj, D., Lipinski, M., and VASSETZKY, Y.S. (2006) Chromatin loop domain organization within the 4q35 locus in facio-scapulo-humeral dystrophy patients versus normal human myoblasts. Proc. Natl. Acad. Sci. USA, 103:6982-6987. pdf 

Lemaître, J.-M., Danis, E., Pasero, P., VASSETZKY, Y, and Méchali, M. (2005) Mitotic remodeling of the replicon. Cell, 123: 787-801. pdf

 

 

Chromatin, Development and Cancer
Yegor Vassetzky, PhD, DSc 
UMR-8126
Institut Gustave Roussy
39, rue Camille-Desmoulins
94805 Villejuif
Tel: 
Fax: 
http://vassetzky.com

Email: vassetzky@igr.fr
ICQ # 31675345